Exemplary histological images of subcutaneously implanted collagen-based bilayer barrier membrane (Bio-Gide®) at three timepoints: 10 days (first row: A,B.1,B.2,C.1,C.2), 30 days (second row: D,E.1,E.2,F.1,F.2), and 60 days (third row: G,H.1,H.2,I.1,I.2). Stretched black arrow: compact layer of the membrane, stretched dotted arrow: loose layer of the membrane, CT: connective tissue, M: membrane, black arrows: macrophages, red arrows: blood vessels, green arrows: granulocytes, grey arrows: lymphocytes, yellow arrows: fibroblasts (HE-stainings, 10×, 20×, and 40× objective magnifications with scale bars: 100 µm, 50 µm, and 20 µm, respectively).