Table 4.
Fever incidence and fever duration as the primary endpoints, sub-grouped according to age 1.
| KB290 + βC | Placebo | RR | 95% CI | p-Value | |
|---|---|---|---|---|---|
| Fever incidence | |||||
| Aged ˂ 40 years | 51/539 (9.5%) | 74/538 (13.8%) | 0.655 | 0.449; 0.957 | 0.028 |
| Aged ≥ 40 years | 60/541 (11.1%) | 35/530 (6.6%) | 1.764 | 1.141; 2.727 | 0.010 |
| Fever duration | |||||
| Aged ˂ 40 years | 1.5 ± 1.0 | 1.7 ± 0.9 | - | - | 0.018 |
| Aged ≥ 40 years | 2.0 ± 1.2 | 1.8 ± 1.2 | - | - | 0.66 |
1 Values in “fever incidence” are expressed as incidence/total number of subjects. The percent sign (%) indicates the rate of fever incidence. Values in “fever duration” are expressed as average days (mean ± SD).