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. 2021 Sep 20;10(9):2487. doi: 10.3390/cells10092487

Figure 3.

Figure 3

SynCav1 preserves synaptic mitochondrial number and morphology in PSAPP mice. (A) Representative images of synaptic mitochondria in CA1 distal apical dendrites within the stratum radiatum with high magnification of representative region at 12 m. Quantitation of synaptic mitochondrial number and area (B,C) and % of total mitochondria relative to the area (D). Representative image and quantification (E,F) of mitochondria-containing pre-synaptic terminal. Data are presented as mean ± S.E.M., n = 5–7 animals per group with 10 micrographs per animal. Data were analyzed using One-Way ANOVA. Significance was assumed when p < 0.05. * p < 0.05, ** p < 0.01, **** p < 0.0001.