Table 5.

Correlations between biomarkers and the severity of individual hangover symptoms on the alcohol day.

	5-HTOL		5-HIAA		5-HTOL/5-HIAAA Ratio
Hangover Symptoms	r	p-Value	r	p-Value	R	p-Value
Headache	0.272	0.125	0.524	0.001 *	0.090	0.619
Nausea	0.322	0.068	0.490	0.003	0.188	0.295
Concentration problems	0.297	0.093	0.489	0.003	0.113	0.530
Regret	0.338	0.054	0.473	0.004	0.172	0.337
Sleepiness	0.254	0.154	0.327	0.055	0.172	0.339
Heart beating	0.256	0.150	0.475	0.004	0.111	0.540
Vomiting	0.263	0.139	0.430	0.010	0.113	0.532
Being tired	0.223	0.213	0.326	0.056	0.135	0.455
Shivering/shaking	0.380	0.029	0.202	0.244	0.319	0.070
Clumsiness	0.275	0.121	0.188	0.279	0.219	0.220
Weakness	0.192	0.284	0.282	0.101	0.129	0.475
Dizziness	0.274	0.123	0.321	0.060	0.163	0.364
Apathy	0.235	0.188	0.270	0.117	0.131	0.466
Sweating	0.158	0.379	0.171	0.326	0.101	0.574
Stomach pain	0.144	0.424	0.356	0.036	0.078	0.666
Confusion	0.317	0.073	0.320	0.061	0.216	0.228
Sensitivity to light	0.096	0.594	0.148	0.395	0.032	0.861
Thirst	0.118	0.512	0.304	0.076	0.039	0.830
Heart racing	0.273	0.124	0.242	0.162	0.201	0.262
Anxiety	0.116	0.519	0.235	0.174	0.034	0.853
Depression	0.131	0.468	0.265	0.123	0.047	0.797
Reduced appetite	0.312	0.077	−0.059	0.737	0.360	0.040

Spearman’s correlations (r) and p-values are shown. Significant correlations (p < 0.0023, after Bonferroni’s correction for multiple comparisons) are indicated by *. Abbreviations: BAC = blood alcohol concentration, 5-HTOL = 5-hydroxytryptophol, 5-HIAA = 5-hydroxyindoleacetic acid.