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. 2021 Sep 16;13(9):1486. doi: 10.3390/pharmaceutics13091486

Table 2.

Physical characteristics of CPEs.

Measured Value Cellactose® 80 CombiLac® MicroceLac® 100 StarLac®
MPS—LD [µm] 184.05 157.25 158.27 146.8
MPS—SA [µm] 326.11 444.44 203.22 173.43
D10 [µm] 51.39 47.37 42.46 26.80
D50 [µm] 183.41 156.09 153.39 146.21
D90 [µm] 309.20 263.17 269.86 266.7
SSA [m2/g] 0.90 1.00 1.00 0.70
Fw [g/s] 11.41 ± 0.05 16.49 ± 0.22 7.40 ± 0.04 18.02 ± 0.12
Θr [o] 32.68 ± 0.67 33.85 ± 0.36 24.66 ± 0.56 26.28 ± 0.33
Θs [o] 32.00 ± 1.00 28.67 ± 0.58 31.67 ± 0.58 29.33 ± 0.58
HR 1.17 ± 0.00 1.10 ± 0.04 1.15 ± 0.01 1.12 ± 0.01
CI 14.83 ± 0.25 9.08 ± 3.49 13.23 ± 0.78 10.41 ± 0.89
ff 20 47 62 27
DB [g/cm3] 0.39 ± 0.00 0.47 ± 0.02 0.49 ± 0.00 0.58 ± 0.00
DT [g/cm3] 0.46 ± 0.00 0.52 ± 0.00 0.56 ± 0.00 0.65 ± 0.00
DP [g/cm3] 1.568 ± 0.003 1.558 ± 0.001 1.567 ± 0.002 1.543 ± 0.001
P [%] 75.20 ± 0.07 69.56 ± 1.13 68.91 ± 0.26 62.42 ± 0.28
M [%] 1.44 ± 0.04 1.76 ± 0.01 1.14 ± 0.01 1.27 ± 0.19
UF3 [%] 50.21 ± 0.01 53.62 ± 0.01 62.18 ± 0.01 33.08 ± 0.00
UF24 [%] 44.36 ± 0.06 48.60 ± 0.07 44.00 ± 0.16 30.00 ± 0.05
pH 6.69 6.82 6.69 6.86

MPS—LD: mean particle size using laser diffraction; MPS—SA: mean particle size using sieve analysis, D10, D50, D90—the diameters of a sample at the 10th, 50th, and 90th percentiles of the cumulative percent undersize plot; SSA—specific surface area; Fw—flow through the orifice; θr—angle of repose (tg α); θs—angle of slide; HR—Hausner ratio; CI—compressibility index; ff—flow function, DB—bulk density; DT—tapped density; DP—pycnometric density; P—porosity; M—moisture content; UF3—undissolved fraction after 3 min; UF24—undissolved fraction after 24 h; pH—(2% solution).