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. 2021 Sep 16;13(9):1486. doi: 10.3390/pharmaceutics13091486

Table 4.

Properties of compacts.

Measured Value CP [MPa] Cellactose® 80 CombiLac® MicroceLac® 100 StarLac®
UM [mg] 78 198.81 ± 1.50 197.66 ± 7.57 199.78 ± 1.35 199.25 ± 0.93
130 199.20 ± 0.74 198.08 ± 2.75 200.70 ± 0.34 197.73 ± 1.98
182 196.96 ± 4.35 198.96 ± 2.22 199.51 ± 0.43 196.48 ± 2.57
78 - - - -
RMS [nm] 130 - - - -
182 202.13 ± 122.59 196.08 ± 91.94 130.58 ± 76.30 180.85 ± 119.66
PD [g/cm3] 78 1.55088 ± 0.0004 1.54436 ± 0.0001 1.5536 ± 0.0002 1.53477 ± 0.0012
130 1.54804 ± 0.0004 1.54201 ± 0.0001 1.5501 ± 0.0002 1.53629 ± 0.0009
182 1.54662 ± 0.0002 1.543001 ± 0.0003 1.5542 ± 0.0002 1.53819 ± 0.0011
Po [%] 78 25.56 ± 2.27 23.45 ± 2.05 23.68 ± 1.21 19.86 ± 1.16
130 18.66 ± 0.77 15.77 ± 2.34 17.40 ± 1.65 15.06 ± 3.32
182 15.21 ± 2.86 11.77 ± 1.34 13.23 ± 1.68 13.45 ± 2.01
He [mm] 78 4.46 ± 0.11 4.41 ± 0.09 4.33 ± 0.06 4.28 ± 0.06
130 4.11 ± 0.03 4.03 ± 0.09 4.02 ± 0.07 3.99 ± 0.15
182 3.87 ± 0.04 3.83 ± 0.04 3.84 ± 0.07 3.88 ± 0.05
Fr [%] 78 1.83 2.86 0.33 4.79
130 1.30 3.01 0.15 6.69
182 3.23 0.83 0.23 5.07
Di [min] 78 0.13 ± 0.00 0.35 ± 0.02 0.27 ± 0.10 0.68 ± 0.07
130 0.28 ± 0.02 0.37 ± 0.03 1.72 ± 0.70 0.73 ± 0.12
182 0.48 ± 0.13 0.55 ± 0.03 1.78 ± 0.70 0.72 ± 0.15
T1 [min] 78 0.12 ± 0.00 0.27 ± 0.02 0.70 ± 0.55 0.15 ± 0.02
130 0.28 ± 0.05 0.25 ± 0.07 0.97 ± 0.33 0.18 ± 0.02
182 0.97 ± 0.40 0.60 ± 0.35 2.23 ± 1.40 0.15 ± 0.02
T2 [min] 78 0.22 ± 0.03 0.43 ± 0.05 1.25 ± 0.45 0.18 ± 0.00
130 0.53 ± 0.05 0.65 ± 0.17 2.90 ± 1.32 0.33 ± 0.07
182 1.65 ± 0.60 1.20 ± 0.55 9.68 ± 5.05 0.28 ± 0.07
WA [%] 78 93.76 ± 3.85 59.59 ± 1.20 63.98 ± 5.75 36.57 ± 4.76
130 96.65 ± 3.11 66.28 ± 4.65 59.19 ± 5.55 38.83 ± 2.87
182 101.13 ± 4.75 69.65 ± 2.49 60.90 ± 18.77 37.42 ± 5.28

CP—compression pressure; UM—uniformity of mass; RMS—surface topography and roughness; PD—pycnometric density; Po—porosity of tablets; He—height; Fr—friability; Di—disintegration; T1, T2—wetting time; WA—water absorption ratio.