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. 2021 Sep 2;13(9):3089. doi: 10.3390/nu13093089

Table 5.

Weighted ORs (95% CI) for score on CERAD test, Animal Fluency test and DSST across dietary VD intake and serum total 25(OH)D, stratified by gender, NHANES 2011–2014.

CREAD Test Animal Fluency Test Digit Symbol Test
Case/Participants Crude Model 1 Model 2 Case/Participants Crude Model 1 Model 2 Case/Participants Crude Model 1 Model 2
Dietary VD intake (μg/d)
male 432/1217 348/1217 370/1217
≤5.00 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
≤20.75 1.04 (0.66–1.64) 1.04 (0.66–1.64) 1.09 (0.68–1.75) 0.65 (0.35–1.20) 0.64 (0.35–1.17) 0.73 (0.37–1.44) 0.95 (0.58–1.54) 0.93 (0.56–1.53) 0.90 (0.55–1.47)
>20.75 0.79 (0.46–1.36) 0.79 (0.45–1.40) 0.86 (0.44–1.68) 0.34 (0.20–0.57) 0.31 (0.19–0.55) 0.38 (0.22–0.67) 0.36 (0.23–0.58) 0.34 (0.22–0.55) 0.46 (0.26–0.82)
female 286/1217 184/1217 287/1217
≤5.00 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
≤20.75 0.90 (0.61–1.33) 0.88 (0.60–1.27) 0.80 (0.49–1.32) 0.73 (0.50–1.06) 0.70 (0.47–1.03) 0.69 (0.46–1.05) 0.66 (0.41–1.07) 0.62 (0.39–1.00) 0.57 (0.26–1.25)
>20.75 0.66 (0.42–1.02) * 0.62 (0.42–0.93) * 0.81 (0.53–1.23) 0.51 (0.34–0.77) * 0.48 (0.31–0.72) * 0.68 (0.43–1.07) 0.36 (0.23–0.57) * 0.33 (0.21–0.50) * 0.50 (0.30–0.83) *
Dietary VD intake (μg/d)
male 432/1217 348/1217 370/1217
≤5.00 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
>5.00 0.93 (0.62–1.38) 0.93 (0.62–1.40) 1.00 (0.64–1.56) 0.51 (0.30–0.85) * 0.49 (0.30–0.83) * 0.58 (0.33–1.04) 0.68 (0.44–1.03) 0.65 (0.42–1.02) 0.72 (0.47–1.10)
female 286/1217 184/1217 287/1217
≤5.00 432/1217 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
>5.00 0.75 (0.52–1.07) 0.72 (0.52–0.99) * 0.81 (0.54–1.19) 0.59 (0.41–0.85) * 0.56 (0.38–0.81) * 0.68 (0.47–1.00) * 0.47 (0.32–0.69) * 0.44 (0.30–0.63) * 0.53 (0.31–0.93) *
Total 25-Hydroxyvitamin D (nmol/L)
male 431/1342 394/1342 401/1342
≤61.41 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
≤86.30 0.83 (0.59–1.17) 0.84 (0.60–1.18) 0.99 (0.65–1.51) 0.56 (0.39–0.85) * 0.57 (0.38–0.85) * 0.84 (0.54–1.30) 0.44 (0.28–0.68) * 0.44 (0.29–0.68) * 0.84 (0.44–1.61)
>86.30 0.63 (0.43–0.93) * 0.61 (0.41–0.89) * 0.77 (0.46–1.31) 0.46 (0.25–0.84) * 0.44 (0.25–0.79) * 0.65 (0.35–1.23) 0.35 (0.20–0.63) * 0.35 (0.20–0.61) * 0.67 (0.30–1.48)
female 289/1393 427/1393 320/1393
≤61.41 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.) 1.00 (Ref.)
≤86.30 1.09 (0.75–1.58) 1.04 (0.70–1.53) 1.01 (0.67–1.54) 1.03 (0.69–1.55) 0.99 (0.65–1.51) 1.49 (0.93–2.41) 0.84 (0.55–1.29) 0.78 (0.50–1.23) 1.04 (0.61–1.78)
>86.30 0.82 (0.58–1.15) 0.73 (0.50–1.06) 0.75 (0.47–1.20) 0.83 (0.58–1.19) 0.76 (0.53–1.07) 1.30 (0.92–1.83) 0.56 (0.41–0.76) * 0.47 (0.34–0.66) * 0.68 (0.42–1.09)

Binary logistic regression analyses were used to calculate weighted OR values. Reference (Ref.); model 1 adjusted for age and gender; model 2 adjusted for age and gender, race, educational level, marital status, income, body mass index (BMI), season of exam, physical activity level, drinking status, smoking status, hypertension, diabetes, and stroke. Energy was adjusted when we studied the intake of dietary VD. * p-value ≤ 0.05.