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. 2021 Sep 15;12(9):1106. doi: 10.3390/mi12091106

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Several pathological models of the respiratory system based on lung-on-a-chip: (a) the microfluidic chip for studying formation of liquid plugs produced by Tavana et al.; (b) the lung-on-a-chip for quantitative analysis of inflammation-mediated thrombosis at the organ level produced by Jain et al.; (c) the lung-on-a-chip in which virus infection of alveolar epithelial cells was observed produced by Qin et al.; (d) the lung-on-a-chip that simulates smoke-induced COPD produced by Benam et al.; (e) the microfluidic chip in which oxygen concentration gradient was realized produced by Chen et al.. Reproduced with permission from [24,25,71,84,97].

Several pathological models of the respiratory system based on lung-on-a-chip: (a) the microfluidic chip for studying formation of liquid plugs produced by Tavana et al.; (b) the lung-on-a-chip for quantitative analysis of inflammation-mediated thrombosis at the organ level produced by Jain et al.; (c) the lung-on-a-chip in which virus infection of alveolar epithelial cells was observed produced by Qin et al.; (d) the lung-on-a-chip that simulates smoke-induced COPD produced by Benam et al.; (e) the microfluidic chip in which oxygen concentration gradient was realized produced by Chen et al.. Reproduced with permission from [24,25,71,84,97].