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Anticancer effects of a combination treatment with metformin and DCA in a mouse model bearing MH-134 cells. (A) Tumor volume in the combination treatment group at 13–15 days was significantly smaller than that in the control or metformin treatment groups (all, p < 0.05). (B) In the combination treatment group, tumor tissues showed TUNEL-positive staining (400× magnification). * p < 0.05.
