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. 2021 Sep 9;9(9):1914. doi: 10.3390/microorganisms9091914

Table 1.

Resistance phenotype and genotype in the 38 CTX/CAZR Escherichia coli isolates from clinical samples in a Portuguese hospital.

Sample Origin Date (Month Year) Resistance Phenotype a ESBL
Production b
Β-lactamases MLST c Resistant Genes/Integrons d PG e
X1068 Blood March 2017 AMC, CTX, CAZ, CIP, SXT P CTX-M-15, TEM ST131 int1 B2
X1080 Blood July 2018 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15, TEM ST131 int1, tetA B2
X1062 Blood December 2016 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1063 Blood December 2016 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1064 Blood December 2016 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1 B2
X1065 Blood June 2017 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1066 Blood June 2017 AMC, CTX, CAZ, TOB, CIP, GEN P CTX-M-15 ST131 ND B2
X1067 Blood February 2017 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1069 Blood March 2017 AMC, CTX, CAZ, TOB, CIP, GEN P CTX-M-15 ST131 ND B2
X1070 Blood March 2017 AMC, CTX, CAZ, CIP, GEN P CTX-M-15 ST131 ND B2
X1071 Blood April 2017 AMC, CTX, CAZ, TET, TOB, CIP, SXT P CTX-M-15 ST131 int1, tetA B2
X1072 Blood April 2017 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1073 Blood April 2017 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1074 Blood April 2017 AMC, CTX, CAZ, TET, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1, tetA B2
X1075 Blood May 2017 AMC, CTX, CAZ, CIP P CTX-M-15 ST410 ND A
X1076 Blood May 2017 AMC, CTX, CAZ, TET, TOB, CIP P CTX-M-15 ST131 ND B2
X1105 Blood May 2017 AMC, CTX, CAZ, CIP P CTX-M-15 ST410 ND A
X1079 Blood July 2018 AMC, CTX, CAZ, TOB, CIP, GEN, SXT P CTX-M-15 ST131 int1 B2
X1081 Blood August 2018 AMC, CTX, CAZ, TET, TOB, CIP P CTX-M-15 ST131 tetA B2
X1078 Blood July 2018 CTX, TET, CIP, SXT P CTX-M-27 ST131 ND B2
X3158 Urine February 2017 CTX, CAZ, TET, TOB, SXT, S P CTX-M-15 NT ND B2
X3159 Urine February 2017 CTX, CAZ, TOB, CIP, GEN, S P CTX-M-15 NT ND B2
X3160 Urine February 2017 CTX, CAZ, TET, TOB, CIP, GEN, S P CTX-M-15 NT ND B2
X3161 Urine March 2017 CTX, CAZ, TOB, CIP, GEN, S P CTX-M-15 NT ND B2
X3162 Urine April 2017 CTX, CAZ, TOB, CIP, GEN, S P CTX-M-15 NT ND D
X3163 Urine May 2017 CTX, CAZ, TET, CIP, SXT, S P CTX-M-15 NT tetA, tetB D
X3164 Urine May 2017 CTX, CAZ, CIP, SXT, S P CTX-M-15 NT ND B2
X3165 Urine May 2017 CTX, CAZ, CIP, S P CTX-M-15 NT ND B2
X3167 Urine June 2018 CTX, CAZ, TET, TOB, CIP, GEN, SXT, S P CTX-M-15 NT tetA B2
X3168 Urine August 2018 CTX, CAZ, TET, TOB, CIP, GEN, SXT, S P CTX-M-15 NT tetA B2
X3169 Urine August 2018 CTX, CAZ, TOB, CIP, GEN, SXT, S P CTX-M-15 NT tetA B2
X3170 Urine August 2018 CTX, CAZ, TET, CIP, S P CTX-M-15 NT tetB B2
X3173 Urine June 2018 AMC, FOX, CTX, CAZ, IMP, TET, CIP, SXT, S P CTX-M-15, KPC2/3 NT tetB A
X3157 Urine February 2017 CTX, TET, SXT, S P CTX-M-1 NT tetA C
X3155 Urine December 2016 CTX, TOB, CIP, SXT, S P CTX-M-variant NT ND B2
X3166 Urine May 2018 ERT, TOB, CIP, GEN, SXT, S P CTX-M-variant NT ND B2
X3171 Urine December 2016 CTX, TOB, CIP, SXT, S P CTX-M-variant NT ND NC
X3156 Urine June 2017 AMC, FOX, CTX, CAZ, IMP, TET, TOB, CIP, GEN, SXT, S P KPC2/3 NT tetA B2

Legend:a AMC: amoxicillin + clavulanic acid; FOX: cefoxitin; CTX: cefotaxime; CAZ: ceftazidime; CHL: chloramphenicol; CIP: ciprofloxacin; TOB: tobramycin; GEN: gentamicin; SXT: trimethoprim + sulfamethoxazole; S: streptomycin; TET: tetracycline; IMP: imipenem; b P—Positive, N—Negative; c MLST—MultiLocus Sequence Typing; d NT: not tested; ND: not detected; NC: Not concluded; e Phylogroups.