Table 3.

Selected PK parameters following analysis for the steers administered 40 mg/kg florfenicol SC once. The geometric mean and geometric CV% are provided. T_max: time to maximum concentration; C_max: the maximum drug concentration; AUC: area under the time–concentration curve.

		Plasma		ISF		Ileum Ultrafiltrate		Colon Ultrafiltrate
Parameter	Unit	Geometric Mean	Geometric CV%	Geometric Mean	Geometric CV%	Geometric Mean	Geometric CV%	Geometric Mean	Geometric CV%
Tmax	h	2.76	52.33	48.32	180.71	14.63	63.52	15.48	85.09
Cmax	µg/mL	2.4	66.15	0.92	86.69	3.51	22.14	2.77	33.55
AUC	h·µg/mL	206.95	58.19	146.08	39.19	426.40	84.15	140.03	45.81
Half-Life	h	56.95	62.28	100.11	25.42	57.24	98.38	23.09	58.56
Penetration	%			97.62	68.04	302.28	92.28	91.61	25.33