TABLE 1.

Transformation of Rat1 fibroblasts by ErbB1 or ErbB2 homodimers^a

ErbB chimera	No. of foci (± SD) per 100 CFU with AP1510 (nM)
	0	50	100	250	500	1,000
p75.B1.F1	0	0	0	0	0	1
p75.B1.F2	0	2 ± 1	7 ± 3	10 ± 4	8 ± 1	7 ± 1
p75.B2.F1	6 ± 1	6 ± 2	8 ± 1	19 ± 2	47 ± 6	34 ± 10
p75.B2.F2	1	16 ± 3	38 ± 7	55 ± 3	62 ± 9	58 ± 6

^aEach value represents an average of at least three independent experiments.