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. 2021 Aug 30;8(9):753. doi: 10.3390/children8090753

Figure 2.

Figure 2

The main roles of ACE2 are shown in the figure. First, it is the cell-receptor for SARS-CoV and SARS-CoV-2. It is also a peptidase: it can create Ang1–9 starting from AngI and Ang1–7 from AngII. ACE2: angiotensin-converting enzyme 2. Ang: angiotensin. AT1: angiotensin II receptor type 1.