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. 2021 Sep 10;13(9):1439. doi: 10.3390/pharmaceutics13091439

Figure 2.

Figure 2

Effect of spermidine on the detachment of corneal epithelium in a rat model of PM2.5-induced dry eye diseases (DED). (A) Representative images of H&E-stained images of corneal sections. Black arrows indicate the detached and swollen epithelium. Scale bar; 50 μm. (B) The numbers of the detached corneal epithelium of 100 μm2 in five different sections were counted. Each bar indicates mean ± standard deviation (n = 5). The statistical analyses were conducted using analysis of ANOVA-Tukey’s post hoc test between groups. *** p < 0.001 compared to the normal group. ## p < 0.01 and ### p < 0.001 compared to the vehicle group.