Table 2.
Characteristic | MT-A (n = 57) | IVT + MT (n = 81) | p | |
---|---|---|---|---|
Time intervals (min) | Onset-to-needle † | 117.7 ± 38.6 (120.0) (98.5–140.0) | ||
Onset-to-groin puncture † | 209.0 ± 93.4 (184.0) (141–265) | 197.0 ± 63.3 (178.5) (145–229.5) | 0.42 | |
Door intervention center-to-groin puncture † | 78.6 ± 32.9 (79.5) (56–106) | 72.8 ± 27.8 (74) (51.75–91.25) | 0.31 | |
Direct transfer to the CSC † | 89.5 ± 27.7 (85.5) (70.5–105) | 85.5 ± 22.0 (83.0) (72.5–101) | 0.42 | |
Interhospital transfer † | 40.8 ± 22.2 (30.0) (27–50.5) | 47.5 ± 19.2 (40.5) (32.5–56) | 0.35 | |
Groin puncture-to-end of intervention † | 46.8 ± 27.2 (40.0) (28–58) | 46.2 ± 27.3 (38.5) (25–56) | 0.91 | |
Onset-to-end of intervention † | 257.7 ± 98.2 (255) (173–313) | 242.8 ± 67.3 (228.5) (191.5–286) | 0.37 | |
Stent-retriever passes | All patients † | 2.1 ± 1.6 (2) (1–3) | 1.9 ± 1.0 (2) (1–3) | |
1 | 27 (47.4) | 41 (50.6) | 0.88 | |
2 | 14 (24.6) | 19 (23.5) | 1.00 | |
≥3 | 7 (12.3) | 7 (8.7) | 0.58 | |
Recanalization grade | TICI 0 | 6 (10.5) | 2 (2.5) | 0.08 |
TICI 1 | 0 (0) | 2 (2.5) | 0.51 | |
TICI 2a | 9 (15.8) | 14 (17.3) | 1.00 | |
TICI 2b | 14 (24.6) | 25 (30.9) | 0.58 | |
TICI 3 | 28 (49.1) | 38 (46.9) | 0.88 | |
TICI ≥2b | 42 (73.7) | 63 (77.8) | 0.90 | |
sICH occurrence |
All patients | 2 (3.5) | 7 (8.6) | 0.32 |
Pre-stroke mRS ≤ 2 | 1/32 (3.1) | 5/56 (8.9) | 0.41 | |
Unknown symptom onset | 1/22 (4.5) | 2/13 (15.4) | 0.55 | |
Direct transfer to the CSC | 2/45 (4.4) | 4/55 (7.3) | 0.69 | |
Interhospital transfer | 0 (0) | 3/26 (11.5) | ||
Leukoaraiosis | 1/21(4.8) | 5/33 (15.2) | 0.40 | |
IVT | 7 (8.6) | |||
3-month good clinical outcome (mRS 0–2) |
All patients | 21 (36.8) | 21 (25.9) | 0.38 |
Pre-stroke mRS ≤ 2 | 21/32 (65.7) | 19/56 (33.9) | 0.12 | |
Unknown symptom onset | 8/22 (36.4) | 2/13 (15.4) | 0.46 | |
Direct transfer to the CSC | 17/45 (37.8) | 15/55 (27.3) | 0.54 | |
Interhospital transfer | 4/12 (33.3) | 6/26 (23.1) | 0.71 | |
Leukoaraiosis | 5/21 (23.8) | 7/33 (21.2) | 1.00 | |
IVT | 21 (25.9) | |||
3-month mortality (mRS 6) |
All patients | 17 (29.8) | 33 (40.7) | 0.21 |
Day 1–10 | 5/17 (29.4) | 8/33 (24.2) | 0.76 | |
Day 11–30 | 6/17 (35.3) | 11/33 (33.3) | 1.00 | |
Day 31–90 | 6/17 (35.3) | 14/33 (42.4) | 1.00 | |
Pre-stroke mRS ≤ 2 | 7 (21.9) | 19 (33.9) | 0.48 | |
Unknown symptom onset | 8/22 (36.4) | 6/13 (46.2) | 0.75 | |
Direct transfer to the CSC | 12/45 (26.7) | 22/55 (40.0) | 0.42 | |
Interhospital transfer | 5/12 (41.7) | 11/26 (42.3) | 1.00 | |
Leukoaraiosis | 8/21 (38.1) | 15/33 (45.5) | 0.80 | |
IVT | 33 (40.7) |
Data are n (%) for categorical variables or mean ± SD (median) (IQR) for numerical variables †. CSC, Comprehensive Stroke Center; IQR, interquartile range; IVT, intravenous thrombolysis; mRS, modified Rankin scale; MT, mechanical thrombectomy; MT-A, MT alone; n, number of patients; SD, standard deviation; sICH, symptomatic intracerebral hemorrhage; TICI, Thrombolysis in Cerebral Infarction.