Table 3.

Cell-cycle inhibitor mutants.

Organism	CDK Regulator	Construction	Phenotype	Reference
Arabidopsis	KRP1/ICK1	Overexpression	Growth inhibition, cell division and endoreduplication inhibition, CDK activity reduction, morphology alterations	Wang et al. 2000
Arabidopsis	KPR2/ICK2	Overexpression	Growth inhibition, cell division and endoreduplication inhibition, CDK activity reduction, morphology alterations	Sanz et al. 2011
Arabidopsis	SIM	Overexpression	Leaf growth inhibition, mitosis inhibition, CDK activity reduction, increased endoreduplication	Churchman et al. 2006
Arabidopsis		Mutation	Multicellular trichomes due to decrease in endoreduplication, increased leaf area and proliferation	Walker et al. 2000
Arabidopsis	wee1	Mutant/T-DNA insertion	Inhibited growth in stress conditions/DNA damage	De Schutter et al. 2007
Arabidopsis	APC10	Overexpression	Increased growth	Eloy et al. 2010
Arabidopsis	samba	Mutation/T-DNA insertion	Increase in leaves, roots, seeds, cell number and expansion	Eloy et al. 2012
Arabidopsis	myb3r3 and myb3r5	Mutation/T-DNA insertion	Hyperplasia, developmental abnormalities, and irregular cell divisions during embryogenesis	Kobayashi et al. 2015
Arabidopsis	myb3r1 and myb3r4	Mutation/T-DNA insertion	Defective cytokinesis	Haga et al. 2011