TABLE 3.
Gene targeting efficiency in Rad51−/− hRad51K-133R+ DT40 cells
| Locus targeted | No. (%) of clones targeting locus/no. of clones examined
|
||
|---|---|---|---|
| RAD51−/− K-133R+ clone 1 | RAD51−/− K-133R+ clone 2 | Wild type | |
| RAD54B | 1/28 (4) | NDa | 8/33 (24) |
| XRCC2 | 22/63 (35) | ND | 41/52 (79) |
| OVALBUMIN | 1/34 (3) | 4/36 (11) | 23/35 (66) |
ND, not determined.