Figure 5.

Wet lab mechanical stability testing of the iPSCs-based engineered cartilage construct. (a) Cartilage constructs engineered from iPSCs differentiated into chondrocytes. (b,c) Special drill was used to create defects on sheep trochlea. (d) Full-thickness cartilage defect on sheep trochlea. (e) Cartilage construct ready for press-fit transplantation. (f) Cartilage construct seated in the defect. Stable, no protrusion beyond the defect borders. (Cartilage constructs were grown and provided by Wa’el Kafienah, University of Bristol, U.K.).