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. 2021 Sep 21;13(9):1524. doi: 10.3390/pharmaceutics13091524

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematics illustrating the preparation of printable emulsion gels, 3D printing by semi-solid extrusion (SSE), and in vitro digestion of 3D-printed tablets. (a) Drug-loaded lipid-based formulation (LBF) was added to water, followed by (b) a two-step emulsification process. (c) Polymers were added to emulsified LBFs to generate printable emulsion gels. (d) The emulsion gels were 3D-printed by SSE into tablets, and (e) vacuum-dried. (f) 3D-printed tablets were digested in an in vitro lipolysis set-up to quantify the release of free fatty acids (FAs). Figures reproduced with permission from [57].