Table 2.
Study | Method for Flap Creation | Number of Eyes * | Flap Displacement | Epithelial Ingrowth | Local Keratitis (Culture Positive or Negative) | Flap Folds | DLK | TLSS |
---|---|---|---|---|---|---|---|---|
Stulting et al., 1999 [72] | manual (Chiron Automated Corneal Shaper) | 1062 + 182 * (only myopic) | 0.4% (partial in 0.6%) | 1.8% | 0.2% | 0.2% | ||
Lin and Maloney 1999 [49] | manual (Chiron Automated Corneal Shaper) | 1019 | 2.0% | 2.2% | 1.1% | 1.8% | ||
Recep et al., 2000 [101] | manual (Moria micokeratome) | 1481 | 1.42% | |||||
Clare et al., 2011 [87] | manual (Moria One Use-Plus) | 23,997 | 0.033% ** | |||||
Muñoz et al., 2006 [82] | femtosecond (AMO IntraLase 15 and 30 kHz) | 765 | 1.3% | |||||
Stonecipher et al., 2006 [81] | femtosecond (IntraLase) | 5667 | 1.1% | |||||
Sutton and Hodge 2008 [102] | femtosecond (AMO IntraLase 15 and 30 kHz) | 1000 | 0.4% | 0.0% | 0.0% | 0.2% | 0.0% | |
Haft et al., 2009 [55] | femtosecond (AMO IntraLase 15 and 30 kHz) | 4772 | 0.42% | 0.25% | ||||
Clare et al., 2011 [87] | femtosecond (IntraLase FS-60) | 57,241 | 0.003% ** | |||||
de Paula et al., 2012 [78] | femtosecond (AMO IntraLase 60 kHz) | 801 | 12.4% | |||||
Tomita et al., 2013 [76] | femtosecond (Femto LDV–IntraLase 60 kHz) | 818 | 8.17% –37.5% |
* LASIK enhancement procedures; ** difference statistically significant, and more common in hyperopia. One eye lost 2 lines of BCVA. Abbreviations: DLK—diffuse lamellar keratitis; TLSS—transient light sensitivity syndrome.