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. 2021 Aug 26;10(9):2201. doi: 10.3390/cells10092201

Figure 2.

Figure 2

Phenotypic characterization of the vasculature in hypoxic SKOV3 tumor model. (A) Top view of a 3-D vasculature surrounding a tumor section reconstructed from confocal scans after CD31 immunostaining in HUVEC. Blue: nuclei. (B) A vertical volume-rendered cross section reconstructed from confocal images showing a hollow lumen surrounded by an endothelial layer. (C) Top view of a 3-D vasculature surrounding a tumor section reconstructed from confocal scans after immunostaining of VE-cadherin in the tumor model with nuclear counterstain. (D) A vertical, volume-rendered section reconstructed from VE-cadherin confocal scans. Scale bars: (A,C) 250 µm; (B,D) 100 µm.