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Morphological characterization of the vasculature in the hypoxic tumor model. Confocal scans of the vascular cross-sections at (A) z = 0 µm, (B) z = 45 µm, and (C) z = 100 µm, respectively. Scale bars: 50 µm. (D) Vascular diameter and (E) vascular density were maintained over 7 days. (D,E) n = 12, 14, 15, 15, 9, 9, 6, 6 for day 0~7, respectively. N.s.: not significant, with one-way ANOVA.
