Figure 12.

(a) Cancer treatment plan using lipocomplexes. (b) UV−vis spectra of the component of Lp-KR-CCM-A. (c) Primary tumor growth in mice. (d) Primary tumor inoculation to the right side, followed by Lp-KR-CCM-A-based PDT to ablate primary tumor and prevent lung metastasis. (e) In a co-culture method, multiple therapies and irradiation of 4T1-Fluc cells resulted in vitro BMDC maturation. (f) In vivo bioluminescence imaging was used to monitor the fate of inoculated luciferase-expressing 4T1-Fluc cancer cells in mice following multiple therapies for primary tumor ablation and lung metastasis prevention. Reproduced with permission from Ref. [87]. Copyright 2019 American Chemical Society. *: p < 0.05; ***: p < 0.001.