Akt	serine/threonine protein kinase
ALK	anaplastic lymphoma kinase
ATP	adenosine triphosphate
Bcl-2	B-cell lymphoma-2
BRAF	v-raf murine sarcoma viral oncogene homolog B1
bFGF	basic fibroblast growth factor
C797S	EGFR exon 20 P. C797S
CNS	central nervous system
CCDC6	coiled-coil domain containing 6-rearrange during transfection
CSF	colony-stimulating factor
ctDNA	circulating tumor DNA
DCR	disease control rate
EGFR	epidermal growth factor receptor
EGFR-TKIs	epidermal growth factor receptor tyrosine kinase inhibitors
EMT	Epithelial mesenchymal transition
EML4	echinoderm microtubule-associated protein-like-4
ErbB	erythroblastosis oncogene B
ERC1	excision repair cross complementing 1
ex19del	EGFR exon 19 deletion
ex20ins	EGFR exon 20 insertion
FDA	Food and Drug Administration
FGF2	fibroblast growth factor 2
FGFR	fibroblast growth factor receptor
G719X	EGFR exon 18 p.G719X
G796R	EGFR exon 20 p.G796R
G796S/D	EGFR exon 20 p.G796S/D
HER	human epidermal growth factor receptor
HER2	human epidermal growth factor receptor 2
HR	hazard ratio
KRAS	kirsten rat sarcoma
L718Q	EGFR exon p.18 L718Q
L792H	EGFR exon p.20 L792H
L792F/R/Y/V/P/I/S	EGFR exon 20 p.L792F/R/Y/V/P/I/S
L798I	EGFR exon 20 p.L798I
L858R	EGFR exon 21 p. L858R
L861Q	EGFR exon 21 p. L861Q
MAPK	mitogen-activate protein kinase
MET	mesenchymal to epithelial transition factor
mTOR	mammalian target of the rapamycin
mPFS	median progression-free survival
mOS	median overall survival
NCCN	National Comprehensive Cancer Network
NMPA	National Medical Products Administration
NSCLC	non-small cell lung cancer
NTRK	neurotrophic tyrosine receptor kinase
ORR	objective response rate
OS	overall survival
PD-L1	programmed cell death 1 ligand1
PPARγ	Peroxisome proliferator-activated receptor gamma
PFS	progression-free survival
PI3K	phosphatidylinositol-3-kinase
PIK3CA	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PTEN	phosphatase and tensin homology deleted on chromosome 10
RCT	randomized controlled trials
RET	rearrange during transfection
RWS	randomized-withdrawal study
ROS1	c-ros oncogene 1 receptor tyrosine kinase
S768I	EGFR exon 20 p.S768I
SCC	squamous cell carcinoma
SCLC	transformation into small cell lung cancer
SqCC	lung squamous cell carcinoma
SPTBN1	spectrin beta non-erythrocytic 1
TACC3	transforming acidic coiled coil protein 3
T-DM1	Trastuzumab emtansine
TGFR	transforming growth factor receptor
TMP3	thrombopoietin mimetic peptide 3
T790M	EGFR exon 20 p.T790M
VEGF	vascular endothelial growth factor
VEGFR2	vascular endothelial growth factor receptor 2
WHO	World Health Organization