Table 3.

Results of conditional association analyses for C18:1 and C18:2 using SNP markers in the 749.1 kb critical region in SSC12.

					C18:1				C18:2
					Single-Marker Analysis		Conditional Analysis		Single-Marker Analysis		Conditional Analysis
No	1 BP	SNP annotation	2 Allele 1	3 r	4 b	5p-value	6 β	7p-value	4 b	5p-value	6 β	7p-value
1	12:54812172	intron-GAS7	T	−0.443	−0.921	7.52 × 10−07	−0.035	0.852	0.108	5.53 × 10−12	0.030	0.059
2	12:54842795	intron-GAS7	T	0.390	0.443	0.038	−0.474	0.027	−0.056	0.0016	0.022	0.217
3	12:54901488	intron-GAS7	G	−0.382	−0.539	0.003	0.107	0.549	0.045	0.0024	−0.010	0.517
4	12:54929793	intron-GAS7	G	0.638	−1.380	3.24 × 10−18	−0.361	0.027	0.125	7.18 × 10−21	0.036	0.008
5	12:54956054	intron-GAS7	C	*-	2.301	2.45 × 10−33	**-	**-	−0.201	1.37 × 10−35	**-	**-
6	12:55073130	coding-MYH13	A	−0.581	−1.016	5.45 × 10−8	0.221	0.244	0.111	1.31 × 10−12	0.003	0.838
7	12:55093697	intron MYH13	A	−0.354	−0.478	0.020	0.247	0.229	0.031	0.0695	−0.031	0.076
8	12:55120479	3′UTR MYH8	G	−0.548	−1.347	9.75 × 10−14	−0.225	0.225	0.094	6.08 × 10−10	−0.0005	0.975
9	12:55180513	3′UTR MYH4	G	−0.556	−1.337	4.91 × 10−14	−0.236	0.194	0.095	2.08 × 10−10	0.002	0.906
10	12:55229376	exon MYH2	G	0.996	2.203	3.65 × 10−31	† NA	† NA	−0.192	3.42 × 10−33	† NA	† NA
11	12:55262653	exon MYH2	T	0.996	2.251	3.91 × 10−32	† NA	† NA	−0.199	3.73 × 10−35	† NA	† NA
12	12:55351879	intron MYH3	A	0.702	−1.449	1.57 × 10−15	0.031	0.871	0.146	9.72 × 10−22	0.017	0.280
13	12:55373617	5′UTR MYH3	G	0.866	1.865	3.54 × 10−21	−0.020	0.921	−0.189	7.08 × 10−30	−0.024	0.174
14	12:55373707	5′UTR MYH3	2	0.999	2.276	6.88 × 10−33	† NA	† NA	−0.198	4.85 × 10−35	† NA	† NA
15	12:55447604	intron ADPRM	G	0.626	1.730	3.19 × 10−12	0.055	0.827	−0.141	1.31 × 10−11	0.002	0.922
16	12:55463919	intron ADPRM	G	0.946	2.252	7.42 × 10−32	0.119	0.560	−0.194	2.60 × 10−33	−0.008	0.637
17	12:55475542	intron ADPRM	T	−0.630	−1.329	1.03 × 10−16	−0.307	0.061	0.123	8.85 × 10−20	0.034	0.016
18	12:55530321	intron ENSSSCG 00000044652	A	−0.101	−1.559	2.87 × 10−6	−1.201	0.0004	0.065	0.0195	0.035	0.209
19	12:55561243	intron ENSSSCG 00000044652	T	0.106	0.378	0.022	0.205	0.216	−0.017	0.226	−0.002	0.883

¹ Physical map position of SNP markers in the 749.1 kb critical region in SSC12; ² reference allele; ³ LD correlation (r) between the key SNP marker (shaded with grey color; the SNP at 12:54956054) and corresponding SNP markers; ⁴ regression coefficients computed from single-marker analysis; ⁵ p-values computed from single-marker analysis; ⁶ regression coefficients calculated from conditional analysis; ⁷ p-values calculated from conditional analysis; bold characters represent SNP markers showing extremely high LD correlation with the key SNP marker; ^† absence of regression coefficient and significance due to collinearity originating from extremely high LD with the key SNP marker. * We did not calculate the LD correlation because r is the correlation between the key SNP and other SNPs; ** we did not compute the β and p-value of the key SNP marker in the conditional analysis.