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. 2021 Aug 26;12(9):1323. doi: 10.3390/genes12091323

Table 4.

Results of conditional association analyses for C20:4 and MUFAs using SNP markers in the 749.1 kb critical region in SSC12.

C20:4 MUFA
Single-Marker Analysis Conditional Analysis Single-Marker Analysis Conditional Analysis
No 1 BP SNP annotation 2 Allele 1 3 r 4 b 5p-value 6 β 7p-value 4 b 5p-value 6 β 7p-value
1 12:54812172 intron-GAS7 T −0.443 0.145 3.30 × 1011 0.031 0.164 −1.021 4.32 × 107 0.204 0.694
2 12:54842795 intron-GAS7 T 0.390 −0.089 0.0003 0.025 0.324 0.543 0.0197 0.234 0.060
3 12:54901488 intron-GAS7 G −0.382 0.076 0.0002 −0.004 0.861 −0.572 0.0033 0.195 0.537
4 12:54929793 intron-GAS7 G 0.638 0.182 2.24 × 1022 0.050 0.010 −1.458 1.80 × 1017 0.176 0.027
5 12:54956054 intron-GAS7 C *- −0.305 9.66 × 1042 **- **- 2.404 3.30 × 1031 **- **-
6 12:55073130 coding-MYH13 A −0.581 0.154 1.43 × 1012 −0.003 0.909 −1.108 5.52 × 108 0.191 0.354
7 12:55093697 intron MYH13 A −0.354 0.059 0.014 −0.031 0.193 −0.479 0.032 0.294 0.189
8 12:55120479 3′UTR MYH8 G −0.548 0.157 1.32 × 1013 0.016 0.452 −1.389 1.59 × 1012 −0.202 0.314
9 12:55180513 3′UTR MYH4 G −0.556 0.160 1.19 × 1014 0.022 0.310 −1.383 6.56 × 1013 −0.222 0.260
10 12:55229376 exon MYH2 G 0.996 −0.289 2.77 × 1038 NA NA 2.302 3.74 × 1029 NA NA
11 12:55262653 exon MYH2 T 0.996 −0.299 2.58 × 1040 NA NA 2.357 3.50 × 1030 NA NA
12 12:55351879 intron MYH3 A 0.702 0.209 6.64 × 1023 0.018 0.421 −1.613 3.45 × 1016 −0.066 0.745
13 12:55373617 5′UTR MYH3 G 0.866 −0.272 8.39 × 1032 −0.022 0.383 2.025 3.13 × 1021 0.054 0.809
14 12:55373707 5′UTR MYH3 2 0.999 −0.301 5.67 × 1041 NA NA 2.381 7.35 × 1031 NA NA
15 12:55447604 intron ADPRM G 0.626 −0.228 3.51 × 1015 −0.016 0.586 1.836 1.09 × 1011 0.053 0.849
16 12:55463919 intron ADPRM G 0.946 −0.291 5.64 × 1038 −0.008 0.758 2.348 1.23 × 1029 0.120 0.587
17 12:55475542 intron ADPRM T −0.630 0.178 4.09 × 1021 0.045 0.020 −1.404 5.31 × 1016 −0.328 0.064
18 12:55530321 intron
ENSSSCG
00000044652
A −0.101 0.127 9.33 × 104 0.084 0.030 −1.444 0.0001 −1.062 0.004
19 12:55561243 intron
ENSSSCG
00000044652
T 0.106 −0.034 0.079 −0.012 0.523 0.376 0.036 0.193 0.285

1 Physical map position of SNP markers in the 749.1 kb critical region in SSC12; 2 reference allele; 3 LD correlation between the key SNP marker (shaded with grey color; the SNP at 12:54956054) and corresponding SNP markers; 4 regression coefficients computed from single-marker analysis; 5 p-values computed from single-marker analysis; 6 regression coefficients calculated from conditional analysis; 7 p-values calculated from conditional analysis; bold characters represent SNP markers showing extremely high LD correlation with the key SNP marker; absence of regression coefficients and significance due to collinearity originated from extremely high LD with the key SNP marker. * We did not calculate the LD correlation because r is the correlation between the key SNP and other SNPs; ** We did not compute the β and p-value of the key SNP marker in the conditional analysis.