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. 2021 Sep 15;13(9):1474. doi: 10.3390/pharmaceutics13091474
3D three dimensional
BBB blood-brain barrier
iBMECs human brain microvascular endothelial cells derived from iPSCs
BMECs brain microvascular endothelial cells
CNS central nervous system
CsA cyclosporine A
DAPI 4′,6-diamidino-2-phenylindole
ECM extracellular matrix
GFAP glial fibrillary acidic protein
GLUT-1 glucose transporter
iPSC induced pluripotent stem cells
LC-MS liquid chromatography and mass spectrometry
MRP multidrug-resistance-associated protein
NVU neurovascular unit
PDMS polydimethylsiloxane
P-gp P-glycoprotein
R123 rhodamine 123
TEER trans-endothelial electrical resistance
TJs tight junctions
UPLC ultra-performance liquid chromatography
ZO-1 zona occludens-1
α-SMA alpha-smooth muscle actin