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. 2021 Aug 31;11(9):1582. doi: 10.3390/diagnostics11091582

Table 4.

Comparison of the average performance matrix and confusion matrix from five-fold cross-validation for (A) Individual top 10 feature, (B) Combined top 1 to 10 features.

(A)
Features AUC Accuracy Precision Recall F1 Score Specificity
Age 0.81 0.85 ± 0.04 0.86 ± 0.03 0.85 ± 0.04 0.85 ± 0.04 0.56 ± 0.05
Lymphocyte count 0.71 0.72 ± 0.10 0.75 ± 0.08 0.72 ± 0.06 0.72 ± 0.07 0.55 ± 0.17
D-Dimer 0.65 0.66 ± 0.08 0.67 ± 0.13 0.66 ± 0.04 0.65 ± 0.07 0.80 ± 0.14
Creatinine 064 0.62 ± 0.02 0.64 ± 0.02 0.62 ± 0.08 0.61 ± 0.06 0.80 ± 0.04
CRP 0.61 0.57 ± 0.05 0.57 ± 0.05 0.57 ± 0.04 0.57 ± 0.04 0.59 ± 0.09
HTN 0.61 0.65 ± 0.04 0.65 ± 0.04 0.65 ± 0.13 0.65 ± 0.07 0.66 ± 0.10
Kidney 0.60 0.54 ± 0.09 0.54 ± 0.08 0.54 ± 0.11 0.54 ± 0.09 0.50 ± 0.10
Heart 0.60 0.61 ± 0.09 0.69 ± 0.06 0.61 ± 0.06 0.56 ± 0.06 0.28 ± 0.14
Abs Neutrophil 0.59 0.61 ± 0.011 0.62 ± 0.09) 0.61 ± 0.014 0.60 ± 0.10 0.48 ± 0.14
GI_Symp 0.58 0.57 ± 0.03 0.57 ± 0.03 0.57 ± 0.05 0.56 ± 0.04 0.71 ± 0.03
(B)
Features Overall Accuracy Weighted Performance with 95% CI Confusion Matrix
Death Alive
Precision Recall F 1 Score Specificity TP FP FN TN
Top 1 feature 0.85 ± 0.04 0.86 ± 0.03 0.85 ± 0.04 0.85 ± 0.04 0.56 ± 0.05 25 24 34 301
Top 2 features 0.91 ± 0.03 0.92 ± 0.03 0.91 ± 0.03 0.91 ± 0.03 0.76 ± 0.04 36 13 22 313
Top 3 features 0.91 ± 0.03 0.92 ± 0.03 0.91 ± 0.03 0.91 ± 0.03 0.78 ± 0.04 37 12 22 313
Top 4 features 0.9 ± 0.03 0.91 ± 0.03 0.9 ± 0.03 0.9 ± 0.03 0.74 ± 0.04 35 14 24 311
Top 5 features 0.92 ± 0.03 0.93 ± 0.02 0.92 ± 0.03 0.93 ± 0.03 0.83 ± 0.04 40 9 20 315
Top 6 features 0.92 ± 0.03 0.93 ± 0.03 0.92 ± 0.03 0.92 ± 0.03 0.81 ± 0.04 39 10 21 314
Top 7 features 0.91 ± 0.03 0.92 ± 0.03 0.91 ± 0.03 0.91 ± 0.03 0.78 ± 0.04 37 12 23 312
Top 8 features 0.91 ± 0.03 0.92 ± 0.03 0.91 ± 0.03 0.92 ± 0.03 0.8 ± 0.04 38 11 22 313
Top 9 features 0.92 ± 0.03 0.93 ± 0.03 0.92 ± 0.03 0.92 ± 0.03 0.8 ± 0.04 38 11 20 315
Top 10 features 0.91 ± 0.03 0.92 ± 0.03 0.91 ± 0.03 0.92 ± 0.03 0.78 ± 0.04 37 12 21 314