Table 1.
Characteristics of patients eligible for blood collection, according to the tumor histotype, initial tumor volume, age and bleomycin dose given in treatment with electrochemotherapy and tumor response after 2 months according to RECIST 1.1 criteria.
| Patient No. | Gender | Age at ECT (Years) | Localization | Histology | Number of Treated Lesions |
Bleomycin Dose (IU) | Response at 2 Months | Tumor Volume (cm3) |
|---|---|---|---|---|---|---|---|---|
| 1 | M | 45 | Skin | SCC | 1 | 30,000 | CR | 0.6 |
| 2 | M | 59 | Skin | SCC | 1 | 24,000 | Lost to FU | 20.5 |
| 3 | M | 35 | Skin | BCC | 1 | 30,000 | PR | 17.7 |
| 4 | F | 39 | Skin | BCC | 1 | 24,000 | CR | 3.5 |
| 5 | M | 49 | Skin | SCC | 4 | 30,000 | CR | 0.3, 14.1, 12.8, 6.3 |
| 6 * | M | 58 | Skin | SCC | 6 | 30,000 | CR | 30.0, 5.6, 0.4, 0.2, 0.2, 19.3 |
| 7 * | M | 49 | Skin | BCC | 1 | 26,000 | CR | 3.8 |
| 8 | M | 59 | Skin | SCC | 1 | 30,000 | CR | 5.2 |
| 9 | F | 50 | Skin | BCC | 1 | 25,000 | CR | 10.6 |
| 10 | F | 55 | Skin | BCC | 1 | 26,000 | Lost to FU | 0.2 |
| 11 * | M | 63 | Skin | Melanoma | 3 | 29,100 | CR | 0.5, 1.0, 3.8 |
| 12 * | M | 64 | Skin | SCC | 7 | 24,750 | Off study | 0.2, 0.6, 0.8, 0.7, 0.6, 0.9, 0.8 |
| Total = 12 | 3 F/9 M | Median = 52.2 Range = 35–64 |
Mean dose = 27,404 ± 2637 |
BCC—basal cell carcinoma, CR—complete response, FU—follow-up, PR—partial response, SCC—squamous cell carcinoma, * patients also eligible for tumor sample collection.