Table 2.
Antimicrobial activity of selected pure sesquiterpene lactones and chicory extracts dissolved in DMSO.
|
S. aureus VTT E-70045 |
P. aeruginosa VTT E- 96728 |
E. coli VTT E-94564T |
|
|---|---|---|---|
| Standards | |||
| Lactucopicrin 4 mM (1.64 mg/mL) |
++ | + | + |
| Parthenolide 4 mM (1.00 mg/mL) |
++ | + | + |
| 11-β-Dihydrolactucopicrin 4 mM (1.65 mg/mL) |
++ | + | + |
| Lactucin 4 mM (1.11 mg/mL) |
+ | + | + |
| Extracts | |||
| Ci_EtOAc (0.05 mg/mL) |
++ | + | + |
| Ci_H2O (1.00 mg/mL) * |
+ | - | NA |
| Wit_EtOAc (1.00 mg/mL) |
++ | - | NA |
| Wit_H2O (1.00 mg/mL) |
- | - | NA |
| Ci_SFE (1.00 mg/mL) |
+++ | - | NA |
- no activity, + weak, ++ moderate (0.5 log reduction CFU/mL after 48 h), +++ strong (1.0 log reduction CFU/mL after 48 h); NA, not applicable; * dissolved in ethanol.