. 2021 Sep 12;9(9):1940. doi: 10.3390/microorganisms9091940

Table 5.

Mean and standard deviation (SD) and median and interquartile range (IR) of counts (log transformed), proportions and frequencies of detection of target bacterial species according to periodontal status and country. Counts and proportions were calculated considering all samples.

	Periodontal Status (Group)	Country	Counts ^a				Proportions ^a				Frequency ^b
	Periodontal Status (Group)	Country	n	Mean (SD)	Median (IR)	p Value	n	Mean (SD)	Median (IR)	p Value	n (%)	p Value
*Porphyromonas gingivalis*	Health and Gingivitis		48	2.34 (2.66)	0.00 (5.48)	0.014 *	48	5.88 (12.22)	0.00 (6.75)	0.007 *	22 (45.8)	0.006 *
	Periodontitis I-II		53	4.15 (2.51)	5.00 (3.77)	1.000 ^†	53	14.57 (20.67)	3.72 (18.50)	0.512 ^†	40 (75.5)	0.123 ^†
	Periodontitis III-IV		66	3.38 (2.97)	5.00 (6.07)	0.062 ^‡	66	10.28 (15.08)	3.27 (17.29)	0.195 ^‡	38 (57.6)	0.645 ^‡
		Spain	90	4.34 (2.33)	5.12 (1.95)	<0.001 ^§	90	13.28 (17.52)	5.83 (18.16)	<0.001 ^§	72 (80.0)	<0.001 ^§
		Colombia	77	2.14 (2.88)	0.00 (5.60)	<0.001 ^§	77	6.99 (14.93)	0.00 (5.06)	<0.001 ^§	28 (36.4)	<0.001 ^§
*Prevotella intermedia*	Health and Gingivitis		48	3.55 (2.48)	4.15 (5.78)	0.294	48	5.59 (8.59)	0.92 (5.22)	0.497	35 (72.9)	0.978 *
	Periodontitis I-II		53	3.95 (2.11)	4.69 (2.24)		53	4.97 (8.48)	0.90 (5.66)		43 (81.1)	1.000 ^†
	Periodontitis III-IV		66	4.17 (2.30)	5.00 (1.95)		66	7.15 (10.24)	2.33 (12.11)		52 (78.8)	1.000 ^‡
		Spain	90	3.56 (2.14)	4.00 (2.77)	<0.001^§	90	3.16 (6.39)	0.66 (3.33)	<0.001^§	70 (77.8)	0.982 ^§
		Colombia	77	4.35 (2.41)	5.43 (1.75)	<0.001^§	77	9.35 (10.86)	5.11 (13.59)	<0.001^§	60 (77.9)	0.982 ^§
*Tannerella forsythia*	Health and Gingivitis		48	2.33 (2.73)	0.00 (5.58)	0.335	48	3.84 (7.10)	0.00 (5.31)	0.160	21 (43.8)	0.939 *
	Periodontitis I-II		53	1.72 (2.45)	0.00 (4.65)		53	0.89 (1.87)	0.00 (0.79)		18 (34.0)	1.000 ^†
	Periodontitis III-IV		66	1.83 (2.47)	0.00 (4.81)		66	0.87 (1.77)	0.00 (1.02)		24 (36.4)	1.000 ^‡
		Spain	90	1.40 (2.18)	0.00 (4.30)	<0.001 ^§	90	0.57 (1.63)	0.00 (0.65)	<0.001 ^§	27 (30.0)	0.026 ^§
		Colombia	77	2.57 (2.78)	0.00 (5.60)	<0.001 ^§	77	3.09 (5.79)	0.00 (3.70)	<0.001 ^§	36 (46.8)	0.026 ^§
*Parvimonas micra*	Health and Gingivitis		48	1.77 (2.57)	0.00 (5.03)	0.503 *	48	2.34 (6.27)	0.00 (2.41)	0.633 *	16 (33.3)	1.000 *
	Periodontitis I-II		53	1.19 (2.23)	0.00 (0.00)	0.275 ^†	53	1.57 (4.12)	0.00 (0.00)	0.271 ^†	12 (22.6)	0.225 ^†
	Periodontitis III-IV		66	0.52 (1.55)	0.00 (0.00)	0.006 ^‡	66	0.57 (2.54)	0.00 (0.00)	0.009 ^‡	7 (10.6)	0.009 ^‡
		Spain	90	0.42 (1.36)	0.00 (0.00)	<0.001 ^§	90	0.28 (1.59)	0.00 (0.00)	<0.001 ^§	8 (8.9)	<0.001 ^§
		Colombia	77	1.88 (2.61)	0.00 (5.14)	<0.001 ^§	77	2.70 (6.04)	0.00 (3.26)	<0.001 ^§	27 (35.1)	<0.001 ^§
*Fusobacterium nucleatum*	Health and Gingivitis		48	4.48 (1.24)	4.69 (1.13)	0.111	48	3.63 (3.37)	2.58 (4.19)	0.951	46 (95.8)	0.822 *
	Periodontitis I-II		53	4.52 (1.74)	5.04 (1.08)		53	4.66 (5.53)	2.45 (5.15)		47 (88.7)	1.000 ^†
	Periodontitis III-IV		66	4.54 (1.91)	5.00 (1.14)		66	8.24 (13.55)	2.65 (9.20)		58 (87.9)	0.564 ^‡
		Spain	90	4.16 (1.58)	4.60 (1.04)	<0.001 ^§	90	2.58 (2.90)	1.95 (2.97)	<0.001 ^§	81 (90.0)	0.842 ^§
		Colombia	77	4.94 (1.71)	5.39 (1.19)	<0.001 ^§	77	9.52 (12.57)	4.17 (9.06)	<0.001 ^§	70 (90.9)	0.842 ^§
*Campylobacter rectus*	Health and Gingivitis		48	0.23 (0.91)	0.00 (0.00)	0.876	48	0.18 (0.88)	0.00 (0.00)	0.849	3 (6.3)	1.000 *
	Periodontitis I-II		53	0.20 (1.03)	0.00 (0.00)		53	0.53 (3.42)	0.00 (0.00)		2 (3.8)	1.000 ^†
	Periodontitis III-IV		66	0.20 (0.94)	0.00 (0.00)		66	0.07 (0.37)	0.00 (0.00)		3 (4.5)	1.000 ^‡
		Spain	90	0.39 (1.28)	0.00 (0.00)	<0.001 ^§	90	0.46 (2.70)	0.00 (0.00)	<0.001 ^§	8 (8.9)	0.008 ^§
		Colombia	77	0.00 (0.00)	0.00 (0.00)	<0.001 ^§	77	0.00 (0.00)	0.00 (0.00)	<0.001 ^§	0 (0.0)	0.008 ^§
*Eikenella corrodens*	Health and Gingivitis		48	1.03 (1.89)	0.00 (2.25)	0.048 *	48	0.35 (0.91)	0.00 (0.09)	0.039 *	12 (25.0)	0.051 *
	Periodontitis I-II		53	0.37 (1.18)	0.00 (0.00)	1.000 ^†	53	0.07 (0.37)	0.00 (0.00)	1.000 ^†	5 (9.4)	1.000 ^†
	Periodontitis III-IV		66	0.47 (1.53)	0.00 (0.00)	0.074 ^‡	66	0.45 (1.85)	0.00 (0.00)	0.066 ^‡	6 (9.1)	0.033 ^‡
		Spain	90	0.66 (1.53)	0.00 (0.00)	0.343 ^§	90	0.19 (0.75)	0.00 (0.00)	0.355 ^§	15 (16.7)	0.241 ^§
		Colombia	77	0.53 (1.60)	0.00 (0.00)	0.343 ^§	77	0.43 (1.70)	0.00 (0.00)	0.355 ^§	8 (10.4)	0.241 ^§
Capnocytophaga spp.	Health and Gingivitis		48	2.36 (2.74)	0.00 (5.43)	0.727	48	3.30 (6.31)	0.00 (4.24)	0.889	21 (43.8)	1.000 *
	Periodontitis I-II		53	2.55 (2.77)	0.00 (5.30)		53	4.94 (11.23)	0.00 (4.47)		25 (47.2)	1.000 ^†
	Periodontitis III-IV		66	2.31 (2.61)	0.00 (5.12)		66	4.14 (11.22)	0.00 (3.33)		30 (45.5)	1.000 ^‡
		Spain	90	0.74 (1.68)	0.00 (0.00)	<0.001 ^§	90	0.15 (0.63)	0.00 (0.00)	<0.001 ^§	15 (16.7)	<0.001 ^§
		Colombia	77	4.34 (2.31)	5.30 (1.39)	<0.001 ^§	77	8.83 (13.34)	4.17 (9.34)	<0.001 ^§	61 (79.2)	<0.001 ^§
*Actinomyces odontolyticus*	Health and Gingivitis		48	2.24 (2.94)	0.00 (5.71)	0.374	48	6.95 (10.96)	0.00 (12.56)	0.278	18 (37.5)	1.000 *
	Periodontitis I-II		53	2.14 (2.81)	0.00 (5.37)		53	5.82 (9.97)	0.00 (10.62)		20 (37.7)	0.399 ^†
	Periodontitis III-IV		66	2.14 (2.81)	4.15 (5.63)		66	10.48 (17.67)	0.65 (16.12)		34 (51.5)	0.414 ^‡
		Spain	90	0.00 (0.00)	0.00 (0.00)	<0.001 ^§	90	0.00 (0.00)	0.00 (0.00)	<0.001 ^§	0 (0.00)	<0.001 ^§
		Colombia	77	5.35 (1.59)	5.69 (1.24)	<0.001 ^§	77	17.33 (15.95)	13.87 (20.47)	<0.001 ^§	72 (93.5)	<0.001 ^§

n, number of patients; n (%), number and percentage of positive samples. *, health and gingivitis group versus periodontitis I-II group; ^†, periodontitis I-II group versus periodontitis III-IV group; ^‡, health and gingivitis group versus periodontitis III-IV group; ^§, Spain versus Colombia. ^a, Kruskal–Wallis test and Mann–Whitney test. ^b, chi-square with Bonferroni correction.