Figure 6.
The effect of dynasore on the reorganization of the Golgi in MCMV infected cells. Δm138-MCMV infected cells were treated with dynasore (80 µM; Dy) at 4 hpi or left untreated (Ø), and at 6 and 14 hpi proceeded for immunofluorescence. (A) Immunofluorescence images of Grasp65 (red), GM130 (green), Golgin97 (red), and IE1 (blue) at 6 and 14 hpi. (B) The percentage of MCMV infected cells (IE1-positive) with the perinuclear ring-like pattern of Grasp65, GM130, and Golgin97. The data represent the mean from 3 independent experiments, and error bars show standard deviations. The significance of differences to untreated samples of the same kinetics was determined using the Student’s t-test (*** p < 0.001, ** p < 0.01, * p < 0.05).