Table 3.

A univariate analysis of the EMT transcription factor expression and the clinicopathological features of 95 PTC patients. In parentheses is the number of patients. The median values of the mRNA fold change between PTC tissue and its normal counterpart are listed for each category of clinical parameters, except for patients’ ages, for which the correlation coefficients are reported. pT, tumor size; pN, lymph node metastasis: TNM, Tumor, Node, Metastasis staging system.

	Twist1	p	Snail1	p	Snail2	p	Zeb1	p	Zeb2	p
Gender
Male (n = 19)  Female (n = 76)	0.94 1.21	0.42	0.38 0.36	0.72	0.58 0.69	0.72	0.60 0.77	0.21	0.56 0.68	0.38
Age (year) Corr. Coeff.	−0.124	0.23	−0.111	0.29	−0.088	0.40	−0.076	0.47	−0.022	0.84
Histology
Classical Variant (n = 72)  Other Variants (n = 23)	1.14 0.97	0.70	0.37 0.32	0.82	0.60 0.82	0.50	0.72 0.84	0.40	0.66 0.79	0.65
BRAF
Wild Type (n = 38)  V600E (n = 38)	0.68 1.35	0.06	0.55 0.31	0.09	0.53 0.84	0.04	0.66 0.66	0.69	0.56 0.73	0.85
pT
T1–2 (n = 39)  T3–4 (n = 56)	1.04 1.09	0.88	0.42 0.33	0.16	0.68 0.62	0.75	0.80 0.60	0.33	0.55 0.78	0.42
pN
N0 (n = 56)  N1 (n = 39)	1.14 0.98	0.40	0.34 0.36	0.58	0.69 0.61	0.90	0.79 0.58	0.31	0.72 0.66	0.73
TNM Stage
I–II (n = 60)  III–IV (n = 35)	1.25 0.79	0.36	0.37 0.36	0.50	0.66 0.61	0.98	0.78 0.72	0.61	0.58 0.79	0.31
Recurrences
No (n = 63)  Yes (n = 16)	0.79 1.40	0.47	0.39 0.32	0.58	0.69 0.70	0.71	0.72 0.58	0.45	0.64 0.49	0.60