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. 2021 Sep 17;10(9):1484. doi: 10.3390/antiox10091484

Figure 1.

Figure 1

Impact of CIH on (A) the animals’ growth curves for body weight, (B) food intake, and (C) water intake. The CIH animals showed (A) a disruption of the growth curve for body weight, (B) a slight decrease in food consumption particularly in the period of HTN development, and (C) a decrease in drink consumption in long-term CIH. Data are presented as variation of body weight from baseline. Two-way ANOVA with Bonferroni’s multiple comparison test; comparison Nx vs. CIH: * p < 0.05; ** p < 0.01; *** p < 0.001. Number of animals per group: Day of study (n for Nx; n for CIH): D7 (33; 31), D14 (25; 26), D21 (20; 20), D28 (12; 14), D35 (12; 14) and D42 to D60 (6; 6). CIH: chronic intermittent hypoxia; Nx: normoxia.