Figure 6.

P17 Model Timeline. On P17, animals were administered 3 mg/kg LPS before undergoing bilateral carotid artery ligation, with the RCA occlusion being reversed after the gas exposure (hypoxia-hyperoxia-hypoxia). Special care was taken to isolate the artery away from surrounding vessels and nerves. Treatment was then initiated within a 90–120 min time window after the end of the HIH insult. Basic reflexes were assessed from P21 to P32 followed by a battery of late behavioral testing on P42. The brains were then extracted and processed for further evaluation.