Table 1.
Single nucleotide polymorphisms (SNPs) in the Chga gene between WKY rats (WKY/Izm) and SHRs (SHR/Izm) using Brown Norway rats as a reference genome.
| Strain Alleles | ||||||||
|---|---|---|---|---|---|---|---|---|
| Izm | NCrlCrlj [14] | |||||||
| Domain | Location | BN | WKY | SHR | Location | BN | WKY | SHR |
| Promoter | A-1600T | A | T | T | A-1616T | A | A | T |
| Promoter | C-161T | C | T | T | C-177T | C | C | T |
| Promoter | C-43T | C | C | T | C-59T | C | C | T |
| Exon 7 | C+8850T | C | T | C | n/a | |||
| Exon 8 | G+11184T | G | T | T | G+11177T | G | G | T |
n/a: The substitution corresponding to the C+8850T mutation has not been reported previously. SNP, single nucleotide polymorphism; BN, Brown Norway; SHR, spontaneously hypertensive rat; WKY, Wistar–Kyoto; Chga, gene encoding chromogranin A.