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Structural change in CYP2A6.25 and CYP2A6.26 (A–D). The wild types, CYP2A6.25, and CYP2A6.26 are shown in cyan, green, and marine, respectively. Nitrogen, oxygen, and hydrogen are displayed in blue, red, and white, respectively, in the stick model. Iron is shown as an orange sphere by a model written as van der Waals radius. The red arrows indicate the shift in CYP2A6.25 and CYP2A6.26. The hydrogen atoms are omitted except for Those of Arg128.
