Figure 3.

Incorporation of label from metabolism of [1,6-¹³C]glucose into newly synthesized lactate (LAC C3) and alanine (ALA C3) in brain from adult WT (white bars) and SIRT3 KO mice (gray bars). Values are mean ± SEM nmol ¹³C incorporated/mg protein from n = 9 WT and 8 SIRT3 KO mice. Individual data points are indicated by circles and triangles. Data were analyzed by Student’s t-test; no differences were found.