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. 2021 Sep 18;22(18):10103. doi: 10.3390/ijms221810103

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Correlation matrix of different synergy metrics and combination sensitivity scores (CSSs) using (A) Pearson and (B) Spearman correlation coefficients. CI = combination index derived from Chou–Talalay model; IC = inhibitory concentration killing the corresponding percentage of MCF7 cells. Colour indicates the correlation coefficient along with negative correlations in blue and positive correlations in red, with the size being directly proportional to statistical confidence based on p-values.