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. 2021 Sep 18;22(18):10103. doi: 10.3390/ijms221810103

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Flow cytometric assessment of the apoptotic profiles of MCF7 cells after 24 h of treatment with cannabidiol, chemotherapeutic drugs, and their synergistic combinations (A–E). The images are representative of three separate experiments. CBD = cannabidiol: DOC = docetaxel: DOX = doxorubicin: PTX = paclitaxel: SN−38: VIN = vinorelbine. (A) CDOC = CBD + DOC, (B) CDOX = CBD + DOX, (C) CPTX = CBD + PTX, (D) CSN–38 = CBD + SN–38, (E) CVIN = CBD + VIN. Cells were treated with the monotherapies, combinations, and vehicle control (0.5% DMSO), and detected using antibodies against Annexin V-CF Blue and the reporter 7AAD after 24 h of treatment. Raw data are available in Table S3.