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Dose-dependent inhibitory effects of polydatin on MAPK and PI3K/AKT signaling pathway in HCT116 and HT-29 cells. Each protein’s phosphorylation level was quantified with each total protein. The asterisks signify statistical variation among polydatin-treated and vehicle-treated groups (* p < 0.05, ** p < 0.01, and *** p < 0.001).
