Table 4.
Curcumin effects on redox status of hyperthyroid-induced animal models.
| Species | Organ | Investigated Aspect | Results | Reference |
|---|---|---|---|---|
| rat | cerebral cortex and cerebellum | lipid peroxidation and SOD activity | ↓ to control values of elevated levels of lipid peroxidation ↑ activity of SOD and of the translated products of SOD1 and SOD2 |
[63] |
| rat | renal cortex | modulation of antioxidant enzymes (i.e., reduced GSH and ascorbic acid, SOD, CAT) and OS parameters (i.e., lipid peroxidation and protein carbonylation) | restored control values levels of OS parameters and small antioxidant molecules ↑ SOD and CAT |
[64] |
| rat | liver | lipid peroxidation and antioxidant genes expression | alleviation of lipid peroxidation and up-regulation of antioxidant genes | [65,66,67] |
CAT: catalase; SOD: superoxide dismutase; GSH: glutathione reductase.