Table 5.
Renal Insufficiency | ||||||
---|---|---|---|---|---|---|
No n = 309 |
Yes n = 41 |
OR | 95% CI | p | ||
n (%) | n (%) | |||||
Cisplatin dose | ||||||
low-dose 1 | 217 (92.7) | 17 (7.3) | ||||
high-dose | 92 (79.3) | 24 (20.7) | 2.73 | 1.33 | 5.63 | 0.006 |
Chemotherapeutic agents | ||||||
cisplatin 1 | 194 (91.5) | 18 (8.5) | ||||
cisplatin and doxorubicin | 115 (83.3) | 23 (16.7) | 0.67 | 0.26 | 1.71 | 0.402 |
Resection method P/D eP/D EPP 1 |
69 (89.6) 233 (88.6) 7 (70.0) |
8 (10.4) 30 (11.4) 3 (30.0) |
0.46 0.85 |
0.09 0.19 |
2.25 3.73 |
0.335 0.827 |
Induction chemotherapy | ||||||
no 1 | 207 (90.0) | 23 (10.0) | ||||
yes | 102 (85.0) | 18 (15.0) | 1.04 | 0.50 | 2.19 | 0.913 |
Cytoprotection | ||||||
no 1 | 162 (94.2) | 10 (5.8) | ||||
yes | 147 (82.6) | 31 (17.4) | 8.36 | 2.37 | 29.49 | 0.001 |
Perioperative fluid balancing | ||||||
no | 28 (82.4) | 6 (17.6) | ||||
yes 1 | 281 (88.9) | 35 (11.1) | 6.33 | 1.57 | 25.45 | 0.009 |
The results of multivariable binary logistic regression analysis (Χ2 = 31.3, p < 0.001, Nagelkerkes R2 = 0.166) and descriptive distribution of risk factors for renal insufficiency are presented. 1 reference category.