For 12 patients started beyond the therapeutic target (a) Distinction of voriconazole trough concentration in different CYP2C19 phenotype groups (n = 50, p = 0.021). The Kruskal–Wallis test was used to compare Cmins. (b) Distinction of voriconazole trough concentration in different groups of C0, C1, Css (n = 50), and daily dose (n = 27). Data are expressed as the median ± interquartile range. (c) The mean concentration of such 12 patients changed by days. (d) Every dosage adjustment (n = 247) and the mode dose (n = 45) by days (It showed the highest one if there were more than one mode). *1, *2, *3, *17 reprented the single nucleotide sequence of genotype of CYP2C19.