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. 2021 Sep 7;10(9):1429. doi: 10.3390/antiox10091429

Figure 2.

Figure 2

Effects of aging and thioredoxin (TRX) on COPD pathology. Cellular aging accelerates COPD progression through structural remodeling, telomere attrition, inflammatory aging, redox dysregulation and protease and anti-protease imbalance. TRX has therapeutic potential for COPD by improving phenomena such as inflamm-aging and redox dysregulation.