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. 2021 Sep 17;10(9):928. doi: 10.3390/biology10090928

Figure 1.

Figure 1

After spinal cord injury (SCI), both chronic systemic inflammation and immunosuppression result in SCI-induced immune depression syndrome (SCI-IDS). Altered immune function results in increased susceptibility to infection and exacerbated secondary complications of SCI. In turn, these secondary complications and infections may create a feedback loop which amplifies immune dysfunction. Created using BioRender.com accessed on 2 September 2021.