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. 2021 Sep 9;22(18):9746. doi: 10.3390/ijms22189746

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of DHT and diet on body weight and composition, and cardiac and renal hypertrophy. Animals were treated with dihydrotestosterone (DHT) or vehicle (Veh) and maintained in low (LFD) or high (HFD) fat diet for 90 days. (A) Body weight was determined by gravimetry. (B) Fat mass was determined by EchoMRI. Left ventricle (LV) (C) and kidney (D) weights were determined by gravimetry and corrected by tibia length (TL). Data are expressed as mean ± SEM. N = 8/group. Data were analyzed by two-way ANOVA followed by Fisher’s LSD test. ^a p < 0.05 vs. LFD-Veh; ^b p < 0.05 vs. HFD-Veh; ^c p < 0.05 vs. LFD-DHT.