Table 3.
Analysis of association rules to comorbidity in patients with mood disorders.
| Rules | N | Support | Confidence | Lift | IS Scale |
|---|---|---|---|---|---|
| Mood disorders (n = 7709) | |||||
| E10–E14→I10–I15 | 262 | 0.034 | 0.504 | 4.635 | 0.397 |
| I10–I15→E10–E14 | 262 | 0.034 | 0.313 | 4.635 | 0.397 |
| E70–E90→I10–I15 | 96 | 0.012 | 0.478 | 4.394 | 0.234 |
| I10–I15→E70–E90 | 96 | 0.012 | 0.115 | 4.394 | 0.234 |
| I10–I15→K20–K31 | 96 | 0.012 | 0.115 | 1.821 | 0.151 |
| Manic episode (n = 45) | |||||
| R50–R69→H00–H06 | 1 | 0.022 | 1.000 | 45.000 | 1.000 |
| H00–H06→R50–R69 | 1 | 0.022 | 1.000 | 45.000 | 1.000 |
| D60–D64→I30–I52 | 1 | 0.022 | 1.000 | 45.000 | 1.000 |
| I30–I52→D60–D64 | 1 | 0.022 | 1.000 | 45.000 | 1.000 |
| D60–D64→R00–R09 | 1 | 0.022 | 1.000 | 45.000 | 1.000 |
| Bipolar affective disorders (n = 2414) | |||||
| I10–I15→E10–E14 | 38 | 0.016 | 0.309 | 6.970 | 0.331 |
| E10–E14→I10–I15 | 38 | 0.016 | 0.355 | 6.970 | 0.331 |
| Depressive episode (n = 4245) | |||||
| G30–G32→F00–F09 | 54 | 0.013 | 0.844 | 19.361 | 0.496 |
| F00–F09→G30–G32 | 54 | 0.013 | 0.292 | 19.361 | 0.496 |
| E10–E14→I10–I15 | 182 | 0.043 | 0.555 | 4.206 | 0.425 |
| I10–I15→E10–E14 | 182 | 0.043 | 0.325 | 4.206 | 0.425 |
| I60–I69→I10–I15 | 46 | 0.011 | 0.575 | 4.359 | 0.217 |
| Recurrent depressive disorders (n = 827) | |||||
| G30–G32→F00–F09 | 13 | 0.016 | 0.867 | 21.719 | 0.584 |
| F00–F09→G30–G32 | 13 | 0.016 | 0.394 | 21.719 | 0.584 |
| E70–E90→I10–I15 | 20 | 0.024 | 0.690 | 4.354 | 0.324 |
| I10–I15→E70–E90 | 20 | 0.024 | 0.153 | 4.354 | 0.324 |
| E70–E90→E10–E14 | 9 | 0.011 | 0.310 | 3.468 | 0.194 |
| Persistent mood disorders (n = 117) | |||||
| E10–E14, I10–I15→G20–G26 | 2 | 0.017 | 0.667 | 39.000 | 0.816 |
| E00–E07→N30–N39 | 2 | 0.017 | 0.667 | 26.000 | 0.667 |
| N30–N39→E00–E07 | 2 | 0.017 | 0.667 | 26.000 | 0.667 |
| G20–G26→E10–E14 | 2 | 0.017 | 1.000 | 19.500 | 0.577 |
| E10–E14→G20–G26 | 2 | 0.017 | 0.333 | 19.500 | 0.577 |
| Other mood disorders (n = 7) | |||||
| A15–A19→C15–C26 | 1 | 0.143 | 1.000 | 7.000 | 1.000 |
| C15–C26→A15–A19 | 1 | 0.143 | 1.000 | 7.000 | 1.000 |
| A15–A19→I10–I15 | 1 | 0.143 | 1.000 | 7.000 | 1.000 |
| I10–I15→A15–A19 | 1 | 0.143 | 1.000 | 7.000 | 1.000 |
| A15–A19→K70–K77 | 1 | 0.143 | 1.000 | 7.000 | 1.000 |
| Unspecified mood disorders (n = 54) | |||||
| B00–B09→K00–K14 | 1 | 0.019 | 1.000 | 54.000 | 1.000 |
| K00–K14→B00–B09 | 1 | 0.019 | 1.000 | 54.000 | 1.000 |
| D10–D36→M40–M54 | 1 | 0.019 | 1.000 | 54.000 | 1.000 |
| M40–M54→D10–D36 | 1 | 0.019 | 1.000 | 54.000 | 1.000 |
| I30–I52→R00–R09 | 1 | 0.019 | 1.000 | 54.000 | 1.000 |
Abbreviations: IS, interest support; ICD-10 code: A15–A19, tuberculosis; B00-B09, viral infections characterized by skin and mucous membrane lesions; C15–C26, digestive organs; D10–D36, benign neoplasms; D60–D64, aplastic and other anemias; E00–E07, disorders of thyroid gland; E10–E14, diabetes mellitus; E70–E90, metabolic disorders; F00–F09, organic, including symptomatic, mental disorders; G20–G26, extrapyramidal and movement disorders; G30–G32, other degenerative diseases of the nervous system; H00–H06, disorders of eyelid, lacrimal system, and orbit; I10–I15, hypertensive diseases; I30–I52, other forms of heart disease; I60–I69, cerebrovascular diseases; K00–K14, diseases of oral cavity, salivary glands, and jaws; K20–K31, diseases of esophagus, stomach, and duodenum; K70–K77, diseases of liver; M40–M54, dorsopathies; N30–N39, other diseases of the urinary system; R00–R09, symptoms and signs involving the circulatory and respiratory systems; R50–R69, general symptoms and signs.