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. 2021 Sep 15;22(18):9960. doi: 10.3390/ijms22189960

Figure 1.

Figure 1

The hypothalamic-pituitary-adrenal (HPA) axis was influenced by acute severe stress. (A) Changes in cortisol concentrations induced by acute severe stress. (B) Alterations in corticosterone caused by acute severe stress. All data are expressed as means ± SD; * p < 0.05 and ** p < 0.001, n = 6 per group.