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. 2021 Aug 31;11(9):878. doi: 10.3390/jpm11090878

Table 3.

Top Nutraceuticals for Symptoms from Highest Overall Net Benefit Rating to Lowest Overall Net Benefit Rating.

Symptoms Nutraceuticals (Overall Net Benefit Rating)
General benefit, no one particular symptom Fruit/Vegetable Powder Concentrate (1.49), Potassium (1.30), Omega 6 (1.18), Vitamin C (1.05), Vitamin D (1.00), CoQ10 (1.00), High Dose Folinic Acid (1.00), Chromium (0.97), Vitamin E (0.95), Iodine (0.95), General Glutathione (0.92), Moderate Dose Folinic acid (0.92), High Dose Multivitamin (0.91), Folic Acid (0.89), Vitamin B1 (0.85), Vitamin A (not as cod liver oil) (0.85), High Dose Multivitamin for Children/Adults with ASD (0.83), Vitamin B2 (0.81), Vitamin B3 (0.78), Blend of Amino Acids (0.77), Calcium (0.76), Vitamin A (as cod liver oil) (0.75), Zinc (0.74), Generic Child/Adult Multivitamin (0.75), Omega 3 (0.74), Selenium (0.74), Vitamin B5 (0.72), Iron (0.69), Milk Thistle (0.66), Magnesium (0.66), Krill Oil (0.66), Vitamin K (0.65), PSP (0.64), Oral Vitamin B12 (0.64), Evening Primrose Oil (0.63), Oral Glutathione (0.62), Lithium (0.60), Biotin (0.60), Cod Liver Oil (0.55), Flax Seed Oil (0.52), Medium Dose Vitamin B6 (0.52), Oral NAC (0.51), Fish Oil (0.49), Carnitine (0.49), Injected Vitamin B12 (0.48), Taurine (0.47), 5-HTP (0.46), Transdermal Glutathione (0.44), Epsom Salt (0.34), DMG (0.30), GABA (0.25)
Sleep (falling asleep) Melatonin (1.33), 5-HTP (0.61), Tryptophan (0.45), Valerian Root (0.44), Magnesium (0.21)
Cognition High Dose Folinic Acid (0.63), Omega 6 (0.53), Cod Liver Oil (0.43), Omega 3 (0.43), Injected Vitamin B12 (0.42), Oral Vitamin B12 (0.40), Fish Oil (0.39), High Dose Multivitamin for Children/Adults with ASD (0.35), CoQ10 (0.26), High Dose Multivitamin (0.23), Lithium (0.22), Krill Oil (0.21), Moderate Dose Folinic Acid (0.20)
Sleep (staying asleep) Melatonin (0.63), 5-HTP (0.46), Tryptophan (0.32), Valerian Root (0.24)
Aggression/Agitation Epsom Salt (0.54), Lithium (0.22), Magnesium (0.20)
Attention High Dose Folinic Acid (0.54), Omega 6 (0.50), Epsom Salt (0.41), High Dose Multivitamin for Children/Adults with ASD (0.32), Cod Liver Oil (0.30), Omega 3 (0.29), Evening Primrose Oil (0.28), PSP (0.26), Oral Vitamin B12 (0.26), Fish Oil (0.21)
Language/Communication High Dose Folinic Acid (0.45), Injected Vitamin B12 (0.45), Moderate Dose Folinic Acid (0.33), Omega 6 (0.32), General Glutathione (0.32), Oral Vitamin B12 (0.30), Cod Liver Oil (0.25), Omega 3 (0.25), Epsom Salt (0.24), High Dose Multivitamin (0.23), High Dose Multivitamin for Children/Adults with ASD (0.22), Fish Oil (0.21), TMG (0.20)
Constipation Fruit/Vegetable Powder Concentrate (0.53), Magnesium (0.48), Vitamin C (0.22)
Health (fewer illnesses and/or less severe illnesses) Fruit/Vegetable Powder Concentrate (0.53), Vitamin C (0.51), High Dose Multivitamin (0.45), Vitamin D (0.34), Potassium (0.33), Zinc (0.31), High Dose Multivitamin for Children/Adults with ASD (0.29), Vitamin E (0.23)
Anxiety Lithium (0.37), Magnesium (0.33), PSP (0.32), GABA (0.27), Tryptophan (0.26), High Dose Multivitamin for Children/Adults with ASD (0.22)
Social Interaction and Understanding High Dose Folinic Acid (0.36), General Glutathione (0.26), Moderate Dose Folinic Acid (0.26), High Dose Multivitamin for Children/Adults with ASD (0.26), Injected Vitamin B12 (0.26), High Dose Multivitamin (0.23), Oral Vitamin B12 (0.22)
Irritability High Dose Folinic Acid (0.27), Magnesium (0.26), Epsom Salt (0.23), High Dose Multivitamin for Children/Adults with ASD (0.22)
Sensory Sensitivity High Dose Multivitamin for Children/Adults with ASD (0.22), Lithium (0.15), Injected Vitamin B12 (0.12)
Lethargy (easily tired) Carnitine (0.21), Chromium (0.19), Injected Vitamin B12 (0.15)
Depression Epsom Salt (0.18), Tryptophan (0.13), Vitamin D (0.11)
Hyperactivity High Dose Folinic Acid (0.18), High Dose Multivitamin for Children/Adults with ASD (0.13), Magnesium (0.12)
Stimming/Perseveration/Desire for Sameness Evening Primrose Oil (0.14), High Dose Multivitamin for Children/Adults with ASD (0.13), Tryptophan (0.13)
OCD PSP (0.13), Vitamin B3 (0.10), High Dose Folinic Acid (0.09)
Tics/involuntary movements Tryptophan (0.13), Potassium (0.08), High Dose Multivitamin (0.08)
Eczema/Skin problems Biotin (0.12), Vitamin E (0.08), Vitamin D (0.07)
Diarrhea Fruit/Vegetable Powder Concentrate (0.11), Glutamine (0.08), High Dose Multivitamin for Children/Adults with ASD (0.06)
Seizures High Dose Folinic Acid (0.09), Moderate Dose Folinic Acid (0.07), Oral Vitamin B12 (0.01)
Self-Injurious behaviors High Dose Folinic Acid (0.09), Oral Glutathione (0.07), High Dose Multivitamin for Children/Adults with ASD (0.06)
Reflux/Vomiting Epsom Salt (0.06), Milk Thistle (0.05), Vitamin E (0.04)